flat profile, moderate signal –> upregulated profile
variable profile –> bending profile
bending profile –> variable profile
peaking profile –> flat profile, moderate signal
flat profile, moderate signal –> flat profile, low signal
variable profile –> peaking profile
flat profile, low signal –> downregulated profile
flat profile, low signal –> variable profile
upregulated profile –> flat profile, low signal
upregulated profile –> variable profile